RhoGDIβ Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation

The integration of signals involved in deciding the fate of mesenchymal stem cells is largely unknown. We used proteomics profiling to identify RhoGDIβ, an inhibitor of the small G-protein Rho family, as a component that regulates commitment of C3H10T1/2 mesenchymal stem cells to the adipocyte or sm...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Huang, Hai-Yan, Zhang, Wen-Ting, Jiang, Wen-Yan, Chen, Su-Zhen, Liu, Yang, Ge, Xin, Li, Xi, Dang, Yong-Jun, Wen, Bo, Liu, Xiao-Hui, Lu, Hao-Jie, Tang, Qi-Qun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Developmental Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409270/
https://ncbi.nlm.nih.gov/pubmed/25778399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608075
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