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Variable Substrate Preference among Phospholipase D Toxins from Sicariid Spiders
Venoms of the sicariid spiders contain phospholipase D enzyme toxins that can cause severe dermonecrosis and even death in humans. These enzymes convert sphingolipid and lysolipid substrates to cyclic phosphates by activating a hydroxyl nucleophile present in both classes of lipid. The most medicall...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409260/ https://ncbi.nlm.nih.gov/pubmed/25752604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.636951 |
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