Multidomain Human Peroxidasin 1 Is a Highly Glycosylated and Stable Homotrimeric High Spin Ferric Peroxidase

Human peroxidasin 1 (hsPxd01) is a multidomain heme peroxidase that uses bromide as a cofactor for the formation of sulfilimine cross-links. The latter confers critical structural reinforcement to collagen IV scaffolds. Here, hsPxd01 and various truncated variants lacking nonenzymatic domains were r...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Soudi, Monika, Paumann-Page, Martina, Delporte, Cedric, Pirker, Katharina F., Bellei, Marzia, Edenhofer, Eva, Stadlmayr, Gerhard, Battistuzzi, Gianantonio, Boudjeltia, Karim Zouaoui, Furtmüller, Paul G., Van Antwerpen, Pierre, Obinger, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409251/
https://ncbi.nlm.nih.gov/pubmed/25713063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632273
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