Apoptosis Signal-regulating Kinase 1 (ASK1)-p38 Pathway-dependent Cytoplasmic Translocation of the Orphan Nuclear Receptor NR4A2 Is Required for Oxidative Stress-induced Necrosis

p38 mitogen-activated protein kinases (MAPKs) play important roles in various cellular stress responses, including cell death, which is roughly categorized into apoptosis and necrosis. Although p38 signaling has been extensively studied, the molecular mechanisms of p38-mediated cell death are unclea...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Watanabe, Takeshi, Sekine, Shiori, Naguro, Isao, Sekine, Yusuke, Ichijo, Hidenori
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409244/
https://ncbi.nlm.nih.gov/pubmed/25752609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.623280
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