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High Structural Resolution Hydroxyl Radical Protein Footprinting Reveals an Extended Robo1-Heparin Binding Interface

Interaction of transmembrane receptors of the Robo family and the secreted protein Slit provides important signals in the development of the central nervous system and regulation of axonal midline crossing. Heparan sulfate, a sulfated linear polysaccharide modified in a complex variety of ways, serv...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Li, Zixuan, Moniz, Heather, Wang, Shuo, Ramiah, Annapoorani, Zhang, Fuming, Moremen, Kelley W., Linhardt, Robert J., Sharp, Joshua S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409239/
https://ncbi.nlm.nih.gov/pubmed/25752613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.648410
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