Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

Decreased insulin sensitivity, also referred to as insulin resistance (IR), is a fundamental abnormality in patients with type 2 diabetes and a risk factor for cardiovascular disease. While IR predisposition is heritable, the genetic basis remains largely unknown. The GENEticS of Insulin Sensitivity...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Knowles, Joshua W., Xie, Weijia, Zhang, Zhongyang, Chennemsetty, Indumathi, Assimes, Themistocles L., Paananen, Jussi, Hansson, Ola, Pankow, James, Goodarzi, Mark O., Carcamo-Orive, Ivan, Morris, Andrew P., Chen, Yii-Der I., Mäkinen, Ville-Petteri, Ganna, Andrea, Mahajan, Anubha, Guo, Xiuqing, Abbasi, Fahim, Greenawalt, Danielle M., Lum, Pek, Molony, Cliona, Lind, Lars, Lindgren, Cecilia, Raffel, Leslie J., Tsao, Philip S., Schadt, Eric E., Rotter, Jerome I., Sinaiko, Alan, Reaven, Gerald, Yang, Xia, Hsiung, Chao A., Groop, Leif, Cordell, Heather J., Laakso, Markku, Hao, Ke, Ingelsson, Erik, Frayling, Timothy M., Weedon, Michael N., Walker, Mark, Quertermous, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409020/
https://ncbi.nlm.nih.gov/pubmed/25798622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74692
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