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Ddx1 knockout results in transgenerational wild-type lethality in mice

DEAD box 1 (DDX1) is a member of the DEAD box family of RNA helicases which are involved in all aspects of RNA metabolism. DDX1 has been implicated in a variety of biological processes, including 3’-end processing of mRNA, DNA repair, microRNA processing, tRNA maturation and mRNA transport. To study...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Hildebrandt, Matthew R., Germain, Devon R., Monckton, Elizabeth A., Brun, Miranda, Godbout, Roseline
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408975/
https://ncbi.nlm.nih.gov/pubmed/25909345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09829
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