Loss of the Drosophila melanogaster DEAD box protein Ddx1 leads to reduced size and aberrant gametogenesis

Mammalian DDX1 has been implicated in RNA trafficking, DNA double-strand break repair and RNA processing; however, little is known about its role during animal development. Here, we report phenotypes associated with a null Ddx1 (Ddx1(AX)) mutation generated in Drosophila melanogaster. Ddx1 null flie...

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Bibliographische Detailangaben
Veröffentlicht in:Dev Biol
Hauptverfasser: Germain, Devon R., Li, Lei, Hildebrandt, Matthew R., Simmonds, Andrew J., Hughes, Sarah C., Godbout, Roseline
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094483/
https://ncbi.nlm.nih.gov/pubmed/26433063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.09.012
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