Promoting endothelial function by S-nitrosoglutathione through the HIF-1α/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats

BACKGROUND: For stroke patients, stimulating neurorepair mechanisms is necessary to reduce morbidity and disability. Our previous studies on brain and spinal cord trauma show that exogenous treatment with the S-nitrosylating agent S-nitrosoglutathione (GSNO) – a nitric oxide and glutathione metaboli...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Khan, Mushfiquddin, Dhammu, Tajinder S, Matsuda, Fumiyo, Baarine, Mauhammad, Dhindsa, Tejbir Singh, Singh, Inderjit, Singh, Avtar K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408969/
https://ncbi.nlm.nih.gov/pubmed/25945035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S77115
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