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Polycyclic Aromatic Hydrocarbons: From Metabolism to Lung Cancer
Excessive exposure to polycyclic aromatic hydrocarbons (PAHs) often results in lung cancer, a disease with the highest cancer mortality in the United States. After entry into the lung, PAHs induce phase I metabolic enzymes such as cytochrome P450 (CYP) monooxygenases, i.e. CYP1A1/2 and 1B1, and phas...
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| Publicado no: | Toxicol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408964/ https://ncbi.nlm.nih.gov/pubmed/25911656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv040 |
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