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Canakinumab as rescue therapy in familial Mediterranean fever refractory to conventional treatment
Familial Mediterranean fever is an autosomal recessive autoinflammatory disorder mainly affecting Mediterranean populations, which is associated with mutations of the MEFV gene that encodes pyrin. Functional studies suggest that pyrin is implicated in the maturation and secretion of interleukin-1 (I...
保存先:
| 出版年: | Drug Des Devel Ther |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408939/ https://ncbi.nlm.nih.gov/pubmed/25945034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S69117 |
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