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Canakinumab as rescue therapy in familial Mediterranean fever refractory to conventional treatment
Familial Mediterranean fever is an autosomal recessive autoinflammatory disorder mainly affecting Mediterranean populations, which is associated with mutations of the MEFV gene that encodes pyrin. Functional studies suggest that pyrin is implicated in the maturation and secretion of interleukin-1 (I...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408939/ https://ncbi.nlm.nih.gov/pubmed/25945034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S69117 |
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