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Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberi

The proteome of the amoebo-flagellate protozoan Naegleria gruberi is rich in candidate RNA repair enzymes, including 15 putative RNA ligases, one of which, NgrRnl, is a eukaryal homolog of Deinococcus radiodurans RNA ligase, DraRnl. Here we report that purified recombinant NgrRnl seals nicked 3′-OH/...

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Publicat a:RNA
Autors principals: Unciuleac, Mihaela-Carmen, Shuman, Stewart
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408790/
https://ncbi.nlm.nih.gov/pubmed/25740837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.049197.114
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