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Hepatitis B virus preS1 deletion is related to viral replication increase and disease progression

AIM: To investigate the clinical implications of hepatitis B virus (HBV) preS1 deletion. METHODS: We developed a fluorescence resonance energy transfer-based real-time polymerase chain reaction (RT-PCR) that can detect four genotypes (wild type, 15-bp, 18-bp and 21-bp deletion). The PCR method was u...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Lee, Seoung-Ae, Kim, Ki-Jeong, Kim, Hong, Choi, Won-Hyuk, Won, Yu-Sub, Kim, Bum-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408479/
https://ncbi.nlm.nih.gov/pubmed/25945020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i16.5039
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