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Naturally Occurring Mutations in the Nonstructural Region 5B of Hepatitis C Virus (HCV) from Treatment-Naïve Korean Patients Chronically Infected with HCV Genotype 1b

The nonstructural 5B (NS5B) protein of the hepatitis C virus (HCV) with RNA-dependent RNA polymerase (RdRp) activity plays a pivotal role in viral replication. Therefore, monitoring of its naturally occurring mutations is very important for the development of antiviral therapies and vaccines. In the...

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Detalhes bibliográficos
Main Authors: Kim, Dong-Won, Lee, Seoung-Ae, Kim, Hong, Won, You-Sub, Kim, Bum-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906201/
https://ncbi.nlm.nih.gov/pubmed/24489961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087773
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