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Promoter hypermethylation profiling of distant breast cancer metastases

Promoter hypermethylation of tumor suppressor genes seems to be an early event in breast carcinogenesis and is potentially reversible. This makes methylation a possible therapeutic target, a marker for treatment response and/or a prognostic factor. Methylation status of 40 tumor suppressor genes was...

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Détails bibliographiques
Publié dans:Breast Cancer Res Treat
Auteurs principaux: Schrijver, Willemijne A. M. E., Jiwa, Laura S., van Diest, Paul J., Moelans, Cathy B.
Format: Artigo
Langue:Inglês
Publié: Springer US 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408366/
https://ncbi.nlm.nih.gov/pubmed/25841351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3362-y
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