Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive G(s)-G protein signaling in osteoblasts

G protein–coupled receptor (GPCR) signaling in osteoblasts (OBs) is an important regulator of bone formation. We previously described a mouse model expressing Rs1, an engineered constitutively active G(s)-coupled GPCR, under the control of the 2.3-kb Col I promoter. These mice showed a dramatic age-...

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Bibliografiske detaljer
Udgivet i:Exp Cell Res
Main Authors: Wattanachanya, Lalita, Wang, Liping, Millard, Susan M., Lu, Wei-Dar, O’Carroll, Dylan, Hsiao, Edward C., Conklin, Bruce R., Nissenson, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408231/
https://ncbi.nlm.nih.gov/pubmed/25704759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.02.009
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