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In Vivo Magnetic Resonance Studies Reveal Neuroanatomical and Neurochemical Abnormalities in the Serine Racemase Knockout Mouse Model of Schizophrenia
BACKGROUND: Decreased availability of the N-methyl-D-aspartate receptor (NMDAR) co-agonist D-serine is thought to promote NMDAR hypofunction and contribute to the pathophysiology of schizophrenia, including neuroanatomical abnormalities, such as cortical atrophy and ventricular enlargement, and neur...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408217/ https://ncbi.nlm.nih.gov/pubmed/25461193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.10.009 |
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