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Deregulation of the MiR-193b-KRAS Axis Contributes to Impaired Cell Growth in Pancreatic Cancer

Modulation of KRAS activity by upstream signals has revealed a promising new approach for pancreatic cancer therapy; however, it is not clear whether microRNA-associated KRAS axis is involved in the carcinogenesis of pancreatic cancer. Here, we identified miR-193b as a tumor-suppressive miRNA in pan...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Jin, Xianglan, Sun, Yang, Yang, Haiyan, Li, Ji, Yu, Shuangni, Chang, Xiaoyan, Lu, Zhaohui, Chen, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408116/
https://ncbi.nlm.nih.gov/pubmed/25905463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125515
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