Safety of Intracoronary Infusion of 20 Million C-Kit Positive Human Cardiac Stem Cells in Pigs

BACKGROUND: There is mounting interest in using c-kit positive human cardiac stem cells (c-kit(pos) hCSCs) to repair infarcted myocardium in patients with ischemic cardiomyopathy. A recent phase I clinical trial (SCIPIO) has shown that intracoronary infusion of 1 million hCSCs is safe. Higher doses...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Keith, Matthew C. L., Tang, Xian-Liang, Tokita, Yukichi, Li, Qian-hong, Ghafghazi, Shahab, Moore IV, Joseph, Hong, Kyung U., Elmore, Brandon, Amraotkar, Alok, Ganzel, Brian L., Grubb, Kendra J., Flaherty, Michael P., Hunt, Gregory, Vajravelu, Bathri, Wysoczynski, Marcin, Bolli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408046/
https://ncbi.nlm.nih.gov/pubmed/25905721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124227
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