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Use of Stopped-Flow Fluorescence and Labeled Nucleotides to Analyze the ATP Turnover Cycle of Kinesins

The kinesin superfamily of microtubule associated motor proteins share a characteristic motor domain which both hydrolyses ATP and binds microtubules. Kinesins display differences across the superfamily both in ATP turnover and in microtubule interaction. These differences tailor specific kinesins t...

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Dades bibliogràfiques
Publicat a:J Vis Exp
Autors principals: Patel, Jennifer T., Belsham, Hannah R., Rathbone, Alexandra J., Friel, Claire T.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408023/
https://ncbi.nlm.nih.gov/pubmed/25350116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52142
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