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Pharmacokinetics of Dolutegravir When Administered With Mineral Supplements in Healthy Adult Subjects
All commercially available integrase inhibitors are 2-metal binders and may be affected by co-administration with metal cations. The purpose of this study was to evaluate the effect of calcium and iron supplements on dolutegravir pharmacokinetics and strategies (dose separation and food) to attenuat...
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| 出版年: | J Clin Pharmacol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BlackWell Publishing Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407950/ https://ncbi.nlm.nih.gov/pubmed/25449994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.439 |
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