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Pharmacokinetics of Dolutegravir When Administered With Mineral Supplements in Healthy Adult Subjects
All commercially available integrase inhibitors are 2-metal binders and may be affected by co-administration with metal cations. The purpose of this study was to evaluate the effect of calcium and iron supplements on dolutegravir pharmacokinetics and strategies (dose separation and food) to attenuat...
Gorde:
| Argitaratua izan da: | J Clin Pharmacol |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BlackWell Publishing Ltd
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407950/ https://ncbi.nlm.nih.gov/pubmed/25449994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.439 |
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