Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms

BACKGROUND: Protein Kinase C (PKC) dysfunction is implicated in a variety of smooth muscle disorders including detrusor overactivity associated with frequency and urgency of micturition. In this study, we aimed to evaluate the modulatory effects of endogenous PKC-dependent pathways on bladder storag...

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Publicado en:BMC Urol
Autores principales: Hypolite, Joseph A, Chang, Shaohua, Wein, Alan J, Chacko, Samuel, Malykhina, Anna P
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407874/
https://ncbi.nlm.nih.gov/pubmed/25896919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-015-0030-9
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