Spontaneous and evoked contractions are regulated by PKC-mediated signaling in detrusor smooth muscle: involvement of BK channels

Protein kinase C (PKC) and large conductance Ca(2+)-activated potassium channels (BK) are downregulated in the detrusor smooth muscle (DSM) in partial bladder outlet obstruction (PBOO). DSM from these bladders display increased spontaneous activity. This study examines the involvement of PKC in the...

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Detalhes bibliográficos
Main Authors: Hypolite, Joseph A., Lei, Qi, Chang, Shaohua, Zderic, Stephen A., Butler, Stephan, Wein, Alan J., Malykhina, Anna P., Chacko, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Translational Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602715/
https://ncbi.nlm.nih.gov/pubmed/23269650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00639.2011
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