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Metabolic regulation of histone post-translational modifications

Histone post-translational modifications regulate transcription and other DNA-templated functions. This process is dynamically regulated by specific modifying enzymes whose activities require metabolites that either serve as co-substrates or act as activators/inhibitors. Therefore, metabolism can in...

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Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Fan, Jing, Krautkramer, Kimberly A., Feldman, Jessica L., Denu, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407823/
https://ncbi.nlm.nih.gov/pubmed/25562692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500846u
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