Developmentally Regulated Post-Translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition

Nucleoplasmin (Npm) is an abundant histone chaperone in vertebrate oocytes and embryos. During embryogenesis, regulation of Npm histone binding is critical for its function in storing and releasing maternal histones to establish and maintain the zygotic epigenome. Here we demonstrate that Xenopus la...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Onikubo, Takashi, Nicklay, Joshua J., Xing, Li, Warren, Christopher, Anson, Brandon, Wang, Wei-Lin, Burgos, Emmanuel S., Ruff, Sophie E., Shabanowitz, Jeffrey, Cheng, R. Holland, Hunt, Donald F., Shechter, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567554/
https://ncbi.nlm.nih.gov/pubmed/25772360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.038
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