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Refining dosing by oral gavage in the dog: A protocol to harmonise welfare
INTRODUCTION: The dog is a frequently-used, non-rodent species in the safety assessment of new chemical entities. We have a scientific and ethical obligation to ensure that the best quality of data is achieved from their use. Oral gavage is a technique frequently used to deliver a compound directly...
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| Publicado en: | J Pharmacol Toxicol Methods |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407634/ https://ncbi.nlm.nih.gov/pubmed/25575806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vascn.2014.12.007 |
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