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Humanization of the mouse mammary gland by replacement of the luminal layer with genetically-engineered preneoplastic human cells
INTRODUCTION: The cell of origin for estrogen receptor α (ERα) positive breast cancer is probably a luminal stem cell in the terminal duct lobular units. To model these cells we have used the murine myoepithelial layer in the mouse mammary ducts as a scaffold upon which to build a human luminal laye...
Zapisane w:
| Wydane w: | Breast Cancer Res |
|---|---|
| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407301/ https://ncbi.nlm.nih.gov/pubmed/25527189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0504-9 |
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