An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells

INTRODUCTION: About 70% of breast cancers express oestrogen receptor α (ESR1/ERα) and are oestrogen-dependent for growth. In contrast with the highly proliferative nature of ERα-positive tumour cells, ERα-positive cells in normal breast tissue rarely proliferate. Because ERα expression is rapidly lo...

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Bibliografske podrobnosti
Main Authors: Duss, Stephan, André, Sylvie, Nicoulaz, Anne-Laure, Fiche, Maryse, Bonnefoi, Hervé, Brisken, Cathrin, Iggo, Richard D
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929103/
https://ncbi.nlm.nih.gov/pubmed/17573968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1734
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