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An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells
INTRODUCTION: About 70% of breast cancers express oestrogen receptor α (ESR1/ERα) and are oestrogen-dependent for growth. In contrast with the highly proliferative nature of ERα-positive tumour cells, ERα-positive cells in normal breast tissue rarely proliferate. Because ERα expression is rapidly lo...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1929103/ https://ncbi.nlm.nih.gov/pubmed/17573968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1734 |
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