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Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease
The SLX1-SLX4 endonuclease required for homologous recombination and DNA repair in eukaryotic cells cleaves a variety of branched DNA structures. The nuclease subunit SLX1 is activated by association with a scaffolding protein SLX4. At the present time, little is known about the structure of SLX1-SL...
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| Udgivet i: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cell Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407285/ https://ncbi.nlm.nih.gov/pubmed/25753413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.019 |
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