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Statistical Inference for Nanopore Sequencing with a Biased Random Walk Model
Nanopore sequencing promises long read-lengths and single-molecule resolution, but the stochastic motion of the DNA molecule inside the pore is, as of this writing, a barrier to high accuracy reads. We develop a method of statistical inference that explicitly accounts for this error, and demonstrate...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407257/ https://ncbi.nlm.nih.gov/pubmed/25902425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.03.013 |
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