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TLR4 mutation and HSP60-induced cell death in adult mouse cardiac myocytes

Extracellular (ex) HSP60 is increasingly recognized as an agent of cell injury. Previously, we reported that low endotoxin exHSP60 causes cardiac myocyte apoptosis. Our findings supported a role for Toll-like receptor (TLR) 4 in HSP60 mediated apoptosis. To further investigate the involvement of TLR...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Heiserman, J. P., Chen, L., Kim, B. S., Kim, S. C., Tran, A. L., Siebenborn, N., Knowlton, A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406935/
https://ncbi.nlm.nih.gov/pubmed/25716072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-015-0577-0
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