Extracellular Heat Shock Protein 60, Cardiac Myocytes and Apoptosis

RATIONALE: Previously, we have found that changes in the location of intracellular HSP60 are associated with apoptosis. HSP60 has been reported to be a ligand of Toll-like receptor (TLR)4. OBJECTIVE: We hypothesized that extracellular HSP60 (exHSP60) would mediate apoptosis via TLR-4. METHODS AND RE...

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Huvudupphovsmän: Kim, Se-Chan, Stice, James P., Chen, Le, Jung, James S., Gupta, Sanjiv, Wang, Yin, Baumgarten, Georg, Trial, Joann, Knowlton, Anne A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949276/
https://ncbi.nlm.nih.gov/pubmed/19875724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.209643
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