Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153

PURPOSE: Programmed Death-1 (PD-1) and its ligand, PD-L1, are regulators of immune/ inflammatory mechanisms. We explored the potential involvement of PD-1/PD-L1 pathway in the inflammatory response and tissue damage in cardiac injury models. EXPERIMENTAL DESIGN: Ischemic-reperfused and cryoinjured h...

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Bibliographic Details
Published in:PLoS One
Main Authors: Baban, Babak, Liu, Jun Yao, Qin, Xu, Weintraub, Neal L., Mozaffari, Mahmood S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406739/
https://ncbi.nlm.nih.gov/pubmed/25902191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124059
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