Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients

INTRODUCTION: Studies on the role of programmed death-1(PD-1) and its main ligand (PD-L1) during experimental models of sepsis have shown that the PD-1/PD-L1 pathway plays a pathologic role in altering microbial clearance, the innate inflammatory response and accelerated apoptosis in sepsis. However...

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Detalhes bibliográficos
Main Authors: Zhang, Yan, Li, Jinbao, Lou, Jingsheng, Zhou, Ying, Bo, Lulong, Zhu, Jiali, Zhu, Keming, Wan, Xiaojian, Cai, Zailong, Deng, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222003/
https://ncbi.nlm.nih.gov/pubmed/21349174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10059
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