Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients

INTRODUCTION: Studies on the role of programmed death-1(PD-1) and its main ligand (PD-L1) during experimental models of sepsis have shown that the PD-1/PD-L1 pathway plays a pathologic role in altering microbial clearance, the innate inflammatory response and accelerated apoptosis in sepsis. However...

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Hauptverfasser: Zhang, Yan, Li, Jinbao, Lou, Jingsheng, Zhou, Ying, Bo, Lulong, Zhu, Jiali, Zhu, Keming, Wan, Xiaojian, Cai, Zailong, Deng, Xiaoming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222003/
https://ncbi.nlm.nih.gov/pubmed/21349174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10059
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