Accelerated epigenetic aging in Down syndrome

Down Syndrome (DS) entails an increased risk of many chronic diseases that are typically associated with older age. The clinical manifestations of accelerated aging suggest that trisomy 21 increases the biological age of tissues, but molecular evidence for this hypothesis has been sparse. Here, we u...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Horvath, Steve, Garagnani, Paolo, Bacalini, Maria Giulia, Pirazzini, Chiara, Salvioli, Stefano, Gentilini, Davide, Di Blasio, Anna Maria, Giuliani, Cristina, Tung, Spencer, Vinters, Harry V, Franceschi, Claudio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2015
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406678/
https://ncbi.nlm.nih.gov/pubmed/25678027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12325
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