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Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells
Mucociliary clearance and fluid transport along epithelial surfaces are carried out by multiciliated cells (MCCs). Recently, human mutations in Cyclin O (CCNO) were linked to severe airway disease. Here, we show that Ccno expression is restricted to MCCs and the genetic deletion of Ccno in mouse lea...
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| Publicado no: | EMBO J |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406653/ https://ncbi.nlm.nih.gov/pubmed/25712475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490805 |
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