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Repurposing Drugs in Oncology (ReDO)—itraconazole as an anti-cancer agent
Itraconazole, a common triazole anti-fungal drug in widespread clinical use, has evidence of clinical activity that is of interest in oncology. There is evidence that at the clinically relevant doses, itraconazole has potent anti-angiogenic activity, and that it can inhibit the Hedgehog signalling p...
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| Publicado no: | Ecancermedicalscience |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cancer Intelligence
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406527/ https://ncbi.nlm.nih.gov/pubmed/25932045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2015.521 |
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