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Repurposing Drugs in Oncology (ReDO)—itraconazole as an anti-cancer agent

Itraconazole, a common triazole anti-fungal drug in widespread clinical use, has evidence of clinical activity that is of interest in oncology. There is evidence that at the clinically relevant doses, itraconazole has potent anti-angiogenic activity, and that it can inhibit the Hedgehog signalling p...

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Bibliografische gegevens
Gepubliceerd in:Ecancermedicalscience
Hoofdauteurs: Pantziarka, Pan, Sukhatme, Vidula, Bouche, Gauthier, Meheus, Lydie, Sukhatme, Vikas P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cancer Intelligence 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406527/
https://ncbi.nlm.nih.gov/pubmed/25932045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2015.521
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