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Phase I study of cladribine, cytarabine, granulocyte colony stimulating factor (CLAG regimen) and midostaurin and all-trans retinoic acid in relapsed/refractory AML
We conducted a phase 1 study using midostaurin (25 mg or 50 mg orally twice daily), all-trans retinoic acid (ATRA) and CLAG chemotherapy to target multiple pathways in relapsed/refractory AML. 10 patients received the combination and no dose limiting toxicities were observed. Two patients (22%) achi...
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| Опубликовано в: : | Int J Hematol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406413/ https://ncbi.nlm.nih.gov/pubmed/24488798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-014-1503-4 |
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