The impact of FGFR1 and FRS2α expression on sorafenib treatment in metastatic renal cell carcinoma

BACKGROUND: Angiogenesis plays a role in tumor growth and is partly mediated by factors in both the fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF) pathways. Durable clinical responses with VEGF tyrosine kinase inhibitors (TKIs) may be limited by intrinsic tumor resistan...

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Bibliografiska uppgifter
I publikationen:BMC Cancer
Huvudupphovsmän: Ho, Thai H, Liu, Xian-De, Huang, Yanqing, Warneke, Carla L, Johnson, Marcella M, Hoang, Anh, Tamboli, Pheroze, Wang, Fen, Jonasch, Eric
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406182/
https://ncbi.nlm.nih.gov/pubmed/25900027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1302-1
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