Independent roles of Fgfr2 and Frs2α in ureteric epithelium

Mice with conditional deletion of fibroblast growth factor receptor 2 (Fgfr2) in the ureteric bud using a Hoxb7cre line (Fgfr2(UB−/−)) develop severe ureteric branching defects; however, ureteric deletion of fibroblast growth factor receptor substrate 2α (Frs2α), a key docking protein that transmits...

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Bibliographic Details
Main Authors: Sims-Lucas, Sunder, Cusack, Brian, Eswarakumar, Veraragavan P., Zhang, Jue, Wang, Fen, Bates, Carlton M.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2011
Subjects:
Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050660/
https://ncbi.nlm.nih.gov/pubmed/21350013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.062158
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