Disruption of the Golgi apparatus by brefeldin A blocks cell polarization and inhibits directed cell migration.

The role of the Golgi apparatus in the motile activity of fibroblasts was examined with brefeldin A (BFA), which disrupts the Golgi apparatus in a variety of cells. Upon incubation with BFA, Swiss mouse 3T3 fibroblasts lost their typical polarized morphology, in which the leading edge is characteriz...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Bershadsky, A D, Futerman, A H
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5686
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