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Negative symptoms in schizophrenia result from a failure to represent the expected value of rewards: Behavioral and computational modeling evidence

CONTEXT: Negative symptoms are a core feature of schizophrenia, but their pathophysiology remains unclear. OBJECTIVE: Negative symptoms are defined by the absence of normal function. However, there must be a productive mechanism that leads to this absence. Here, we test a reinforcement learning acco...

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Detalhes bibliográficos
Publicado no:Arch Gen Psychiatry
Main Authors: Gold, James M., Waltz, James A., Matveeva, Tatyana M., Kasanova, Zuzana, Strauss, Gregory P., Herbener, Ellen S., Collins, Anne G.E., Frank, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406055/
https://ncbi.nlm.nih.gov/pubmed/22310503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2011.1269
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