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P2Y(2)receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells
INTRODUCTION: Extracellular nucleotides are released and detectable in a high concentration within the tumor microenvironment. G protein-coupled P2Y(2) nucleotide receptor (P2Y(2)R) is activated equipotently by adenosine triphosphate (ATP) and uridine 5′-triphosphate (UTP), which mediate proinflamma...
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Izdano u: | Breast Cancer Res |
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Glavni autori: | , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
BioMed Central
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406012/ https://ncbi.nlm.nih.gov/pubmed/25156554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3694 |
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