P2Y(2)receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells

INTRODUCTION: Extracellular nucleotides are released and detectable in a high concentration within the tumor microenvironment. G protein-coupled P2Y(2) nucleotide receptor (P2Y(2)R) is activated equipotently by adenosine triphosphate (ATP) and uridine 5′-triphosphate (UTP), which mediate proinflamma...

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Enregistré dans:
Détails bibliographiques
Publié dans:Breast Cancer Res
Auteurs principaux: Jin, Hana, Eun, So Young, Lee, Jong Sil, Park, Sang Won, Lee, Jae Heun, Chang, Ki Churl, Kim, Hye Jung
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406012/
https://ncbi.nlm.nih.gov/pubmed/25156554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3694
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