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Loss of sFRP-1 Leads to Deterioration of Cardiac Function in Mice and Plays a Role in Human Cardiomyopathy

BACKGROUND: The Wnt/β-catenin signaling pathway plays a central role during cardiac development and has been implicated in cardiac remodeling and aging. However, the role of Wnt modulators in this process is unknown. In the present study, we examined the role of the Wnt signaling inhibitor sFRP-1 in...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Circ Heart Fail
Κύριοι συγγραφείς: Sklepkiewicz, Piotr, Shiomi, Takayuki, Kaur, Rajbir, Sun, Jie, Kwon, Susan, Mercer, Becky, Bodine, Peter, Schermuly, Ralph Theo, George, Isaac, Schulze, P. Christian, D’Armiento, Jeanine M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405910/
https://ncbi.nlm.nih.gov/pubmed/25669938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001274
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