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Loss of sFRP-1 Leads to Deterioration of Cardiac Function in Mice and Plays a Role in Human Cardiomyopathy

BACKGROUND: The Wnt/β-catenin signaling pathway plays a central role during cardiac development and has been implicated in cardiac remodeling and aging. However, the role of Wnt modulators in this process is unknown. In the present study, we examined the role of the Wnt signaling inhibitor sFRP-1 in...

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Dades bibliogràfiques
Publicat a:Circ Heart Fail
Autors principals: Sklepkiewicz, Piotr, Shiomi, Takayuki, Kaur, Rajbir, Sun, Jie, Kwon, Susan, Mercer, Becky, Bodine, Peter, Schermuly, Ralph Theo, George, Isaac, Schulze, P. Christian, D’Armiento, Jeanine M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405910/
https://ncbi.nlm.nih.gov/pubmed/25669938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001274
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