The Human GATA1 Gene Retains a 5′ Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts

GATA1 is a key transcription factor for erythropoiesis. GATA1 gene expression is strictly regulated at the transcriptional level. While the regulatory mechanisms governing mouse Gata1 (mGata1) gene expression have been studied extensively, how expression of the human GATA1 (hGATA1) gene is regulated...

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Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Moriguchi, Takashi, Yu, Lei, Takai, Jun, Hayashi, Makiko, Satoh, Hironori, Suzuki, Mikiko, Ohneda, Kinuko, Yamamoto, Masayuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405652/
https://ncbi.nlm.nih.gov/pubmed/25755285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00011-15
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